OPTION 1
5Days itinerary
Day 1.

Meet your guides and escorts at RMS Headquarters (1648m) and  start the hike 4-5 hours to Nyabitaba camp (2651m), enjoying wonderful  views over the lush afro-montane forest.
Day 2.

Start for John Maate camp (3505m) 5-7 hours away- walking  through the Bamboo-Mimulopsis zone, the hagenia belt and ending the  day with the heather zone
Day 3.

Start for Bujuku camp (3962m), walking through the heather  zone, the lower and upper Bujuku bogs (now with board walks), enter  the Asanecio and groundsel zone, pass Lake Bujuku and on to the  beautiful Bujuku camp. Walk normally between 4-6 hours.
Day 4.

Bujuku back to Nyabitaba by skipping johnmaate on the way  descending back.(walking 8 hrs 30 min), by walking down the valley of  Bujuku river this Involves descending, steep slopes and rocks and  wadding through this Trail Passing through Mud, crossing rivers and  deep Mud back to Nyabitaba hut.
Day 5:

Nyabitaba Hut and proceed out of the national park. Leave  Nyabitaba hut early retracing out route back to the Rwenzori mountain  services offices. Descend back through the 3 to 4 hours. Continue  descending through Mubuku River and through fields to the Park  Headquarters.
OPTION 2
Suggested 5 day trekking itinerary to climb margherita peak.
Day 1:

Nyakalengijo (1648m). Meet your guides and escorts at RMS  Headquarters and start the hike 4-5 hours to Nyabitaba camp (2651m),  enjoying wonderful views over the lush afro-montane forest (walking  for 5-6 hours)

Day 2:

Nyabitaba hut to Johnmaate (walking 7 hours), up the valley of  Bujuku river.
The last hour of the trekking is a bit more demanding as the trail  starts ascending faster and passes through some boulders/rocks as well.

Day 3:

Johnmaate camp to Bujuku and after proceeds to Elena hut  (walking 7/8hours).
Climb to Elena Camp (at the snout of the glacier), walking through  Asanecio and the wonderful lobelia Wollastonii, then bare rock and  scree with nice views of the valleys below as well as Lake Bujuku.
The last hour of the trekking is a bit more demanding as the trail  starts ascending faster and passes through some muddy and rocks as well.

Day 4.

Scale the Stanley Plateau and the Margherita Glacier to Point  Margherita (5,109 m above sea level) .In reverse, follow the same  route as for the ascent except, at the bottom of Margherita glacier  use the abseil rope/fixed rope for protection and even to aid the  climb to connect to the Stanley plateaux. The ice axe, harness, rope  and the crampons are useful. After the plateaux, scramble down wards  back to Elena camp after a cup of tea proceed to Kitandara camp  through scree slopes and enjoy the beauty of the twin trough lakes of  Kitandara.

Day 5.

Climb over Fresh field pass and descent to Guy Yeoman camp,  bypassing the ancient Rock shelter used by the Duke of Abruzzi in his  1906 classic climb. After some cup of tea, walk down crossing the  Mubuku River through the heathers, mimulopsis and Bamboo zone to  Nyabitaba camp to complete the circuit. After lunch leave Nyabitaba  hut retracing out route back to the Rwenzori mountain services  offices. This trail usually takes 9 to 11 hours. Descending through  Mubuku River and through fields to the Park Headquarters.
OPTION 3
5 Days Central circuit Rwenzori Mountains trekking itinerary
Day 1: 

Nyakalengija (1615m) – Nyabitaba Hut (2651m)
Begin the day by approaching the Rwenzori mountaineering services  (RMS) head offices early in order to hire equipments if so and arrange  for guides, chef and porters. at once hiking starts from the park  headquarters 1,646 meters to Nyabitaba a distance of 10 Km takes 4- 5  hours and an ascent of 1200 meters. The trail at the beginning goes  through homes and fields progressing through bamboo and high elephant  grass, dense bushes. You will climb over rocks and bluff, crossing  river Mahoma then ascending steeply into Nyabitaba. Certain animals  may be spotted such as the white Colobus, blue monkeys, three horned  chameleon and the Rwenzori turaco. Stay overnight at the Nyabitaba hut.
Day 2: 

Nyabitaba (2651m) – Mubuku River (2600m) John Matte Hut (3505m)
From Nyabitaba you descend to your right follow the trail that drops  down through the forest for a half an hour to the Kurt Shafer Bridge,  just below the confluence of the Mubuku and Bujuku rivers. The walk is  then easy going for a couple of hours passing through the bamboo  forest and then becomes more difficult ,kind of like spelunking,  traverse through a long and exhausting stretch of slippery  moss-covered rocks. From the Nyamuleju rock shelter, Mount Stanley and  Mount Speke can be seen before passing into the zone of the giant  heather, lobelia and groundsel. Finally reach John Matte Hut after  passing through the tiring bog. While here, high chances of catching  the nice views of Mt.Stanley and Margherita glacier, finally Dinner  and Overnight at the Hut.

Day 3:

John Matte (3505m) skip Bujuku (3962m) and over night at  Kitandara camp (4023): 6-7hrs
From John Matte Hut the trail drops down to cross the Bujuku River  and enters Lower Bigo Bog, the home of giant lobelias. Jumping from  tussock to tussock, the bog is finally crossed but rarely without the  feet sampling some of the freezing ooze below. Continuing on to the  upper bigo bog you will follow the Bujuku river that sometimes runs  underground from lake Bujuku, with views of Mt Baker to the South and  Mt Stanley to the West. Bujuku Hut, well located in the shadow of  Mount Baker and Mount Speke, is set in a narrow valley below Stuhlmann  Pass. After some lunch at Bujuku, leave for Kitandara camp the trail  takes you through more bog, while climbing the steep slopes west of  the lake and through the magical Groundsel Gully as it ascends to  Scott-Elliot Pass at 4372m., where there are spectacular views back to  Bujuku Lake and Mount Speke, up to Mount Stanley and down to the  Kitandara Lakes. After the trail that passes you through an alpine  zone of sparse vegetation and rough boulders, descend past the  Kitandara Lakes for dinner and overnight at the Kitandara
Day 4: Kitandara (4023m) – Fresh field Pass (4282m) – Guy Yeoman (3505m)
From Kitandara, take on the trail that ascends steeply up the  headwall, spreading out from the base of Mount Baker and continuing  along the south side of the mountain to Fresh field Pass. At this  point you can view into the Congo to the west and Mount Stanley to the  north. From the pass, take on the long trail passing the rock shelter  at Bujongolo, the base camp for the historic expedition by the Duke of  Abruzzi in 1906. Over night at Guy yeoman

Day 5: Guy Yeoman (3505m) – Nyabitaba (2651m) and then straight to  Nyakalengija the base camp (1615m)

The descent to Nyabitaba takes around 6 -7 hours but with an early  start it is possible to make it all the way down to Nyakalengija.  Below Guy Yeoman, the route descends the cliffs of Kichuchu. Beyond  Kichuchu the muddy path crosses the Mubuku River twice before climbing  upwards to Nyabitaba to complete the circuit. After lunch/cup of tea  leave Nyabitaba hut retracing out route back to the Rwenzori mountain  services offices. This 10 Km trail usually takes 2 to 3 hours.  Descending through Mubuku River and through fields to the Park  Headquarters to hand over the rented equipments / Pick up any Luggage  that you may have left here, dinner and overnight to the lodge of your  choice